1. absolute to be lord or master, gain the mastery , (Aeschulus Tragicus)

2. with genitive to be lord or master of , (Homeric Hymns), etc.; δεσπόζειν φόβης to own the lock of hair, (Aeschulus Tragicus); metaphorically to master , δ. λόγου (Aeschulus Tragicus)

3. with accusative to lord it over , (Euripides) (ML)