1. of things, painful, distressing , Lat. molestus, (Herdotus Historicus), attic

2. of persons,

3. in good sense, causing sorrow by one's departure, (Euripides)

4. in bad sense, causing pain, troublesome, vexatious, offensive , (Sophocles Tragicus), etc.

5. adverb λυπηρῶς, painfully, so as to cause pain , (Sophocles Tragicus); λυπηρῶς ἔχει it is painful , (Sophocles Tragicus) (ML)